The El-Sayed Laboratory

90 Rom, J.S., Le Breton, Y., Islam, E., Belew, A.T., El-Sayed, N.M., & McIver, K.S. (2022). Loss of rpoE Encoding the δ-Factor of RNA Polymerase Impacts Pathophysiology of the Streptococcus pyogenes M1T1 Strain 5448. Microorganisms, 10(8), 1686.
89 Burcham, L.R., Akbari, M.S., Alhajjar, N., Keogh, R.A., Radin, J.N., Kehl-Fie, T.E., Belew, A.T., El-Sayed, N.M., McIver, K.S., & Doran, K.S. (2022). Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization. mBio, 13(3), e00985-22.
88 Wang, R., Belew, A.T., Achuthan, V., El-Sayed, N.M., & DeStefano, J.J. (2021). Physiological magnesium concentrations increase fidelity of diverse reverse transcriptases from HIV-1, HIV-2, and foamy virus, but not MuLV or AMV. J. Gen. Virol., 102(12), 001708.
87 Gómez, M.A., Belew, A.T., Navas, A., Rosales-Chilama, M., Murillo, J., Dillon, L.A.L., Alexander, T.A., Martinez-Valencia, A., & El-Sayed, N.M. (2021). Early leukocyte responses in ex-vivo models of healing and non-healing human Leishmania (Viannia) panamensis infections. Front. Cell. Infect. Microbiol., 11(687607), 1-12.
86 Smith, M., Yadav, S., Fagunloye, O.G., Pels, N.A., Horton, D.A., Alsultan, N., Borns, A., Cousin, C., Dixon, F., Mann, V.H., Lee, C., Brindley, P.J., El-Sayed, N.M., Bridger, J.M., & Knight, M. (2021). PIWI silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with Schistosoma mansoni in the snail vector, Biomphalaria glabrata. PLoS Negl. Trop. Dis., 15(9), e0009094.
85 Tavares, T., Mügge, F., Grazielle-Silva, V., Valente, B., Goes, W., Oliveira, A., Belew, A.T., Guarneri, A.A., Pais, F.S., El-Sayed, N.M., & Teixeira, S.M.R. (2021). A Trypanosoma cruzi zinc finger protein that is implicated in the control of epimastigote-specific gene expression and metacyclogenesis. Parasitology, 148(10), 1171-1185.
84 Vargas, D.A., Gregory, D.J., Koren, R.N., Zilberstein, D., Belew, A.T., El-Sayed, N.M., & Gómez, M.A. (2020). Macrophage metallothioneins participate in the antileishmanial activity of antimonials. BioRxiv, (preprint), .
83 Lee, V.T., Ghodssi, R., El-Sayed, N.M., Malik, R., Goloubeva, O.G., Hazen, T.H., & Rasko, D.A. (2020). Draft Genome Sequence of Pseudomonas aeruginosa Strain PA14-UM. Microbiol. Resour. Announc., 9(46), e00978-20.
82 Burcham, L.R., Le Breton, Y., Radin, J.N., Spencer, B.L., Deng, L., Hiron, A., Ransom, M.R., Mendonça, J.D.C., Belew, A.T., El-Sayed, N.M., McIver, K.S., Kehl-Fie, T.E., & Doran, K.S. (2020). Identification of zinc-dependent mechanisms used by Group B Streptococcus to overcome calprotectin-mediated stress. mBio, 11(6), 5460-5472.
81 Hamidzadeh, K., Belew, A.T., El-Sayed, N.M., & Mosser, D.M. (2020). The transition of M-CSF-derived human macrophages to a growth-promoting phenotype. Blood Adv., 4(21), 5460-5472.
80 Oliveira, A.E.R., Pereira, M.C.A., Belew, A.T., Ferreira, L.R.P., Pereira, L.M.N, Neves, E.G.A., Nunes, M.D.C.P., Burleigh, B.A., Dutra, W.O., El-Sayed, N.M., Gazzinelli, R.T., & Teixeira, S.M.R. (2020). Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation. PLoS Path., 16(8), e1008781.
79 Dalby E., Christensen, S.M., Wang J., Hamidzadeh, K., Chandrasekaran, P., Hughitt, V.K., Tafuri, W.L., Arantes, R.M.E., Rodrigues, I.A., Herbst, R., El-Sayed, N.M., Sims, G.P., & Mosser, D.M. (2020). Immune Complex-Driven Generation of Human Macrophages With Anti-Inflammatory and Growth-Promoting Activity. J. Immunol., 205(1), 102-112.
78 Edgar,R.J., van Hensbergen, V.P., Ruda, A., Turner, A.G., Deng, P., Le Breton, Y., El-Sayed, N.M., Belew, A.T., McIver, K.S., McEwan, A.G., Morris, A.J., Lambeau, G., Walker, M.J., Rush, J.S., Korotkov, K.V., Widmalm, G., van Sorge, N.M., Korotkova, N. (2019). Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nat. Chem. Biol., 15(5), 463–471.
77 Christensen, S.M., Belew, A.T., El-Sayed, N.M., Tafuri, W.L., Silveira, F.T., & Mosser, D.M. (2019). Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis. PLoS Neg. Trop. Dis., 13(3), e0007152.
76 Banks, D.A., Ahlbrand, S.E., Hughitt, V.K., Shah, S., Vogel, S.N., El-Sayed, N.M., & Briken, V. (2019). Mycobacterium tuberculosis inhibits autocrine type I interferon signaling to increase intracellular survival. J. Immunol., 202(8), 2348-2359.
75 Valdes, K., Sundar, G.S., Belew, A.T., Islam, E., El-Sayed, N.M., Le Breton, Y., & McIver, K.S. (2018). Glucose levels alter the Mga virulence regulon in the group A Streptococcus. Scientific Reports, 8(1), 1-16.
74 Hossain. M., Alam, M., Khaleque, A., Islam, S., Sadique, A., Khan, N., Halim, Z., Sarker, M., El-Sayed, N.M., Huq, A., Ahsan, G.U., & Colwell, R.R. (2018). Virulence-Related Genes Identified from the Genome Sequence of the Non-O1/Non-O139 Vibrio cholerae Strain VcN1, Isolated from Dhaka, Bangladesh. Genome Announcements, 6(10), e01513-17.
73 Geis-Asteggiante, L., Belew, A.T., Clements, V.K., Edwards, N.J., Ostrand-Rosenberg, S., El-Sayed, N.M., & Fenselau, C. (2018). Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions. J. Proteome Res., 17(1), 486-498.
72 Belew, A.T., Junqueira, C., Rodrigues-Luiz, G.F., Valente, B.M., Oliveira, A.O., Polidoro, R.B., Zuccherato, L.W., Bartholomeu, D.C., Schenkman, S., Gazzinelli, R.T., Burleigh, B.A., El-Sayed, N.M., & Teixeira, S.M.R. (2017). Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection. PLoS Pathogens, 13(12), e1006767.
71 Smircich, P., El-Sayed, N.M., & Garat, B. (2017). Intrinsic DNA curvature contributes indirect DNA readout effects in trypanosomes. BMC Res. Notes, 10(1), 585.
70 Le Breton, Y., Belew, A.T., Freiberg, J.A., Sundar, G.S., Islam, E., Lieberman, J., Shirtliff, M.E., Tettelin, H., El-Sayed, N.M., & McIver, K.S. (2017). Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection. PLoS Pathogens, 13(8), e1006584.
69 Stevens, A.M., Smith, A.C., Marbach-Ad, G., Balcom, S.A., Buchner, J., Daniel, S.L., DeStefano, J.J., El-Sayed, N.M., Frauwirth, K., Lee, V.T., McIver, K.S., Melville, S.B., Mosser, D.M., Popham, D.L., Scharf, B.E., Schubot, F.D., Seyler, R.W., Shields, P.A., Song, W., Stein, D.C., Stewart, R.C., Thompson, K.V., Yang, Z., & Yarwood, S.A. (2017). Using a Concept Inventory to Reveal Student Thinking Associated with Common Misconceptions about Antibiotic Resistance. J. Microbiol. Biol. Educ., 18(1), 10.
68 Inbar, E., Hughitt, V.K., Dillon, L.A.L., Ghosh, K., El-Sayed, N.M., & Sacks, D.L. (2017). The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector. mBio, 8(2), e00029-17.
67 Quigley, J., Hughitt, V.K., Velikovsky, C.A., Mariuzza, R., El-Sayed, N.M., & Briken, V. (2017). The cell wall lipid PDIM mediates phagosomal escape and host cell exit of Mycobacterium tuberculosis. mBio, 8(2), e00148-17.
66 Vega, L.A, Valdes, K.M., Sundar, G.S, Belew, A.T., Islam, E., Berge, J., Curry, P., Chen, S., El-Sayed, N.M., Breton, Y.L., & McIver, K.S. (2017). The transcriptional regulator CpsY is important for innate immune evasion in Streptococcus pyogenes. Infection and Immunity, 85(3), e00925.
B6 Bartholomeu, D., Teixeira, S., & El-Sayed, N.M. (2017). Genetics of Trypanosoma cruzi: Nuclear Genome. In Telleria, J. & Tibayrenc, M. (Eds.), American Trypanosomiasis Chagas Diseases: One Hundred Years of Research (2nd ed., pp. 429-446). Elsevier Press.
65 Christensen, S.M., Dillon, L.A., Carvalho, L.P, Passos, S., Novais, F.O., Hughitt, V.K., Beiting D.P., Carvalho, E.M., Scott, P., El-Sayed, N.M., Mosser, D.M. (2016). Meta-transcriptome profiling of the human-Leishmania braziliensis cutaneous lesion. PLoS Neglected Tropical Diseases, 10(9), e0004992.
64 Houston-Ludlam, G.A., Belew, A.T., & El-Sayed, N.M. (2016). Comparative transcriptome profiling of human foreskin fibroblasts infected with the Sylvio and Y strains of Trypanosoma cruzi. PLoS One, 11(8), e0159197.
63 Fernandes, M.C., Dillon, L.A.L., Belew, A.T., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2016). Dual transcriptome profiling of Leishmania-infected human macrophages reveals distinct reprogramming signatures. mBio, 7(3), e00027-16.
62 Li, Y., Shah-Simpson, S., Okrah, K., Belew, A.T., Choi, J., Caradonna, K.L., Padmanabhan, P., Ndegwa, D. M., Temanni, M.R., Corrada Bravo, H., El-Sayed, N.M., & Burleigh, B.A. (2016). Transcriptome remodeling in Trypanosoma cruzi and human cells during intracellular infection. PLoS Pathogens, 12(4), e1005511.
61 Valdes, K.M., Sundar, G.S., Vega, L.A., Belew. A.T., Islam, E., Binet, R., El-Sayed, N.M., Le Breton, Y., & McIver. K.S. (2016). The fruRBA operon is necessary for Group A Streptococcal growth in fructose and for resistance to neutrophil killing during growth in whole human blood. Infection and Immunity, 84(4), 1016-31.
60 Dillon, L.A.L., Okrah, K., Suresh, R., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2015). Simultaneous transcriptional profiling of Leishmania major parasites and murine macrophages. BMC Genomics, 16, 1108.
59 Dillon, L.A., Okrah, K., Hughitt, V.K., Suresh, R., Li, Y., Fernandes, M.C., Belew, A.T., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2015). Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation. Nucleic Acids Research, 43(14), 6799-813.
58 Fleming, B.D., Chandrasekaran, P., Dillon, L.A., Dalby, E., Suresh, R., Sarkar, A., El-Sayed, N.M., & Mosser, D.M. (2015). The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. Journal of Leukocyte Biology, 98(3), 395-407.
57 Le Breton, Y., Belew, A.T., Valdes, K.M., Islam, E., Curry, P., Tettelin, H., Shirtliff, M.E., El-Sayed, N.M., & McIver, K.S. (2015). Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes. Nature Scientific Reports, 5, 9838.
56 Smircich, P., Forteza, D., El-Sayed, N.M., & Garat, B. (2013). Genomic analysis of sequence-dependent DNA curvature in Leishmania. PLoS One, 8(4), e63068.
55 Savage, A.F., Cerqueira, G.C., Regmi, S., Wu, Y., El-Sayed, N.M., & Aksoy, S. (2012). Transcript expression analysis of putative Trypanosoma brucei GPI-anchored surface proteins during development in the tsetse and mammalian hosts. PLoS Neg. Trop. Dis., 6(6), e1708.
54 Waisberg, M., Cerqueira, G.C., Yager, S.B., Francischetti, I.M., Lu, J., Gera, N., Srinivasan, P., Miura, K., Rada, B., Lukszo, J., Barbian, K.D., Leto, T.L., Porcella, S.F., Narum, D.L., El-Sayed, N.M., Miller, L.H., & Pierce, S.K. (2012). Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P. PNAS, 109(14), 5429-34.
53 Choi, J., & El-Sayed, N.M. (2011). Functional Genomics of Trypanosomatids. Parasite Immunology, 34(2-3), 72-9.
52 Simões, M.C., Lee, J., Djikeng, A., Cerqueira, G.C., Zerlotini, A., da Silva-Pereira, R.A., Dalby, A.R., LoVerde, P., El-Sayed, N.M., & Oliveira, G. (2011). Identification of Schistosoma mansoni microRNAs. BMC Genomics, 12, 47.
B5 Teixeira, S.M., El-Sayed, N.M., & Araújo, P.R. (2011). Chapter 10 - The genome and its implications. In Weiss, L.M., Tanowitz, H.B., & Kirchhoff, L.V. (Eds.), Advances in Parasitology Chagas Disease, Part A (1st ed., pp. 209-30). Elsevier Press.
51 Marbach-Ad, G., McAdams, K., Benson, S., Briken, V., Cathcart, L., Chase, M., El-Sayed, N., Frauwirth, K.,  Fredericksen, B., Joseph , S., Lee, V., McIver, K., Mosser, D., Quimby, B., Shields, P., Song, W., Stein, D., Stewart, R., Thompson, K., & Smith, A. (2010). A Model for Using a Concept Inventory as a Tool for Students' Assessment and Faculty Professional Development. CBE Life Sciences Education, 9(4), 408-16. 408–416
50 Severance, S., Rajagopal, A., Rao, A.U., Cerqueira, G.C., Mitreva, M., El-Sayed, N.M., Krause, M., & Hamza, I. (2010). Genome-wide analysis reveals novel genes essential for heme homeostasis in Caen­rhabditis elegans. PLoS Genetics, 6(7), e1001044.
49 Joseph, S.J., Fernández-Robledo, J.A., Gardner, M.J., El-Sayed, N.M., Kuo, C.H., Schott, E.J., Wang, H., Kissinger, J.C., & Vasta, G.R. (2010). The Alveolate Perkinsus marinus: biological insights from EST gene discovery. BMC Genomics, 11, 228.
B4 Bartholomeu, D., Buck, G., Teixeira, S., & El-Sayed, N.M. (2010). Genetics of Trypanosoma cruzi. In Telleria, J. & Tibayrenc, M. (Eds.), American Trypanosomiasis Chagas Disease: One Hundred Years of Research (1st ed., pp. 433-457). Elsevier Press.
48 Ittiprasert, W., Miller, A., Myers, J., Nene, V., El-Sayed, N.M., & Knight, M. (2009). Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni. Molecular Biochemical Parasitology, 169(1), 27-39.
47 Berriman, M., Haas, B.J., LoVerde, P.T., Wilson, R.A., Dillon, G.P., Cerqueira, G.C., Mashiyama, S.T., Al-Lazikani, B., Andrade, L.F., Ashton, P.D., Aslett, M.A., Bartholomeu, D.C., Blandin, G., Caffrey, C.R., Coghlan, A., Coulson, R., Day, T.A., Delcher, A., DeMarco, R., Djikeng, A., Eyre, T., Gamble, J.A., Ghedin, E., Gu, Y., Hertz-Fowler, C., Hirai, H., Hirai, Y., Houston, R., Ivens, A., Johnston, D.A., Lacerda, D., Macedo, C.D., McVeigh, P., Ning, Z., Oliveira, G., Overington, J.P., Parkhill, J., Pertea, M., Pierce, R.J., Protasio, A.V., Quail, M.A., Rajandream, M.A., Rogers, J., Sajid, M., Salzberg, S.L., Stanke, M., Tivey, A.R., White, O., Williams, D.L., Wortman, J., Wu, W., Zamanian, M., Zerlotini, A., Fraser-Liggett, C.M., Barrell, B.G., & El-Sayed, N.M. (2009). The genome of the blood fluke Schistosoma mansoni. Nature, 460(7253), 352-8.
46 Bartholomeu, D.C., Cerqueira, G.C., Leao, A.C.A., daRocha, W.D., Pais, F.S., Macedo, C., Djikeng, A., Teixeira, S.M.R., & El-Sayed, N.M. (2009). Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruzi. Nucleic Acids Research, 120(4), 357-63.
45 Marbach-Ad, G., Briken, V., El-Sayed, N.M., Frauwirth, K., Fredericksen, B., Hutcheson, S., Gao, L.Y., Joseph, S., Lee, V.T., McIver, K.S., Mosser, D., Quimby, B.B., Shields, P., Song, W., Stein, D.C., Yuan, R.T., & Smith, A.C. (2009). Assessing student understanding of host pathogen interactions using a concept inventory. Journal of Microbiology & Biology Education, 10(1), 43-50.
44 Bringaud, F., Ghedin, E., El-Sayed, N.M., & Papadopoulou, B. (2008). Role of transposable elements in trypanosomatids. Microbes and Infection, 10(6), 575-81.
43 Cerqueira, G.C., Bartholomeu, D.C., Darocha, W.D., Hou, L., Freitas-Silva, D.M., Machado, C.R., El-Sayed, N.M., & Teixeira, S.M. (2008). Sequence diversity and evolution of multigene families in Trypanosoma cruzi. Molecular and Biochemical Parasitology, 157(1), 65-72.
42 Waisberg, M., Lobo, F.P., Cerqueira, G.C., Passos, L.K., Carvalho, O.S., El-Sayed, N.M., & Franco, G.R. (2008). Schistosoma mansoni: Microarray analysis of gene expression induced by host sex. Experimental Parasitology, 120(4), 357-63.
41 Bringaud, F., Müller, M., Cerqueira, G.C., Smith, M., Rochette, A., El-Sayed, N.M., Papadopoulou, B., & Ghedin, E. (2007). Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathogens, 3(9), 1291-307.
40 Ghedin, E., Wang, S., Spiro, D., Caler, E., Zhao, Q., Crabtree, J., Allen, J.E., Delcher, A.L., Guiliano, D.B., Miranda-Saavedra, D., Angiuoli, S.V., Creasy, T., Amedeo, P., Haas, B., El-Sayed, N.M., Wortman, J.R., Feldblyum, T., Tallon, L., Schatz, M., Shumway, M., Koo, H., Salzberg, S.L., Schobel, S., Pertea, M. Pop, M., White, O., Barton, G.J., Carlow, C.K., Crawford, M.J., Daub, J., Dimmic, M.W., Estes, C.F., Foster, J.M., Ganatra, M., Gregory, W.F., Johnson, N.M., Jin, J., Komuniecki, R., Korf, I., Kumar, S., Laney, S., Li, B.W., Li, W., Lindlom, T.H., Lustigman, S., Ma, D., Maina, C.V., Martin, D.M., McCarter, J.P., McReynolds, L., Mitreva, M., Nutman, T.B., Parkinson, J., Peregrin-Alvarez, J.M., Poole, C., Ren, Q., Saunders, L., Sluder, A.E., Smith, K., Stanke, M., Unnasch, T.R., Ware, J., Wei, A.D., Weil, G., Williams, D.J., Williams, S.A., Fraser-Liggett, C., Slatko, B., Blaxter, M.L., & Scott, A.L. (2007). Draft genome of the filarial nematode parasite Brugia malayi. Science, 317(5845), 1756-60.
39 Haas, B.J., Berriman, M., Hirai, H., Cerqueira, G.C, Loverde, P.T., & El-Sayed, N.M. (2007). Schistosoma mansoni genome: Closing in on a final gene set. Experimental Parasitology, 117(3), 225-8.
38 Waisberg, M., Lobo, F.P., Cerqueira, G.C., Passos, L.K., Carvalho, O.S., Franco, G.R., & El-Sayed, N.M. (2007). Microarray analysis of gene expression induced by sexual contact in Schistosoma mansoni. BMC Genomics, 8, 181.
37 Souza, R.T., Santos, M.R.M., Lima, F.M., El-Sayed, N.M., Myler, P.J., Ruiz, J.C., & da Silveira, J.F. (2007). New Trypanosoma cruzi repeated element that shows site specificity for insertion. Eukaryotic Cell, 6(7), 1228-38.
36 Stelter, K., El-Sayed, N.M., & Seeber, F. (2007). The expression of a plant-type ferredoxin redox system provides molecular evidence for a plastid in the early dinoflagellate Perkinsus marinus. Protist, 158(1), 119-30.
35 Djikeng, A., Raverdy, S., Foster, J., Bartholomeu, D., Zhang, Y., El-Sayed, N.M., & Carlow, C. (2007). Cofactor-independent Phosphoglycerate Mutase is an essential gene in procyclic form Trypanosoma brucei. Parasitology Research, 100(4), 887-92.
34 Attardo, G.M., Strickler-Dinglasan, P., Perkin, S.A., Caler, E., Bonaldo, M.F., Soares, M.B., El-Sayed, N.M., & Aksoy, S. (2006). Analysis of fat body transcriptome from the adult tsetse fly, Glossina morsitans morsitans. Insect Molecular Biology, 15(4), 411-24.
33 Westenberger, S.J., Cerqueira, G.C., El-Sayed, N.M., Zingales, B., Campbell, D.A., & Sturm, N.R. (2006). Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and possess a conserved element in the non-coding region. BMC Genomics, 7, 60.
32 Baida, R.C., Santos, M.R., Carmo, M.S., Yoshida, N., Ferreira, D., Ferreira, A.T., El-Sayed, N.M., Andersson, B., & da Silveira, J.F. (2006). Molecular characterization of serine-, alanine-, and proline-rich proteins of Trypanosoma cruzi and their possible role in host cell infection. Infection and Immunity, 74(3), 1537-46.
31 Wu, W., Niles, E.G., El-Sayed, N., Berriman, M., & LoVerde, P. (2006). Schistosoma mansoni (Platyhelminthes, Trematoda) nuclear receptors: sixteen new members and a novel subfamily. Gene, 366(2), 303-15.
30 Bringaud, F., Bartholomeu, D., Blandin, G., Delcher, A., Baltz, T., El-Sayed, N.M., & Ghedin, E. (2006). The Trypanosoma cruzi L1Tc and NARTc non-LTR retrotransposons show relative site specificity for insertion. Molecular Biology and Evolution, 23(2), 411-20.
29 MacLeod, A., Tweedie, A., McLellan, S., Taylor, S., Hall, N., Berriman, M., El-Sayed, N.M., Hope, M., Turner, C.M.R., & Tait, A. (2005). The genetic map and comparative analysis with physical map of Trypanosoma brucei. Nucleic Acids Research, 33(21), 6688-93.
28 Bringaud, F., Ghedin, E., Blandin, G., Bartholomeu, D., Levin, M.J., Baltz, T., & El-Sayed, N.M. (2005). Evolution of non-LTR retrotransposons in the trypanosomatid genomes: Leishmania major lost the active elements. Molecular and Biochemical Parasitology, 145(2), 158-70.
27 Barry, J.D., Marcello, L., Morrison, L.J., Read, A.F., Lythgoe, K., Jones, N., Carrington, M., Blandin, G., Bohme, U., Caler, E., Hertz-Fowler, C., Renauld, H., El-Sayed, N., & Berriman, M. (2005). What the genome sequence is revealing about trypanosome antigenic variation. Biochemical Society Transactions, 33(5), 986-9.
26 El-Sayed, N.M., Myler, P.J., Blandin, G., Berriman, M., Crabtree, J., Aggarwal, G., Caler, E., Renauld, H., Worthey, E.A., Hertz-Fowler, C., Ghedin, E., Peacock, C., Bartholomeu, D.C., Haas, B.J., Tran, A.N., Wortman, J.R., Alsmark, U.C., Angiuoli, S., Anupama, A., Badger, J., Bringaud, F., Cadag, E., Carlton, J.M., Cerqueira, G.C., Creasy, T., Delcher, A.L., Djikeng, A., Embley, T.M., Hauser, C., Ivens, A.C., Kummerfeld, S.K., Pereira-Leal, J.B., Nilsson, D., Peterson, J., Salzberg, S.L., Shallom, J., Silva, J.C., Sundaram, J., Westenberger, S., White, O., Melville, S.E., Donelson, J.E., Andersson, B., Stuart, K.D., & Hall, N. (2005). Comparative genomics of trypanosomatid parasitic protozoa. Science, 309(5733), 404-9.
25 El-Sayed, N.M., Myler, P.J., Bartholomeu, D.C., Nilsson, D., Aggarwal, G., Tran, A.N., Ghedin, E., Worthey, E.A., Delcher, A.L., Blandin, G., Westenberger, S.J., Caler, E., Cerqueira, G.C., Branche, C., Haas, B., Anupama, A., Arner, E., Aslund, L., Attipoe, P., Bontempi, E., Bringaud, F., Burton, P., Cadag, E., Campbell, D.A., Carrington, M., Crabtree, J., Darban, H., da Silveira, J.F., De Jong, P., Edwards, K., Englund, P.T., Fazelina, G., Feldblyum, T., Ferella, M., Frasch, A.C., Gull, K., Horn, D., Hou, L., Huang, Y., Kindlund, E., Klingbeil, M., Kluge, S., Koo, H., Lacerda, D., Levin, M.J., Lorenzi, H., Louie, T., Machado, C.R., McCulloch, R., McKenna, A., Mizuno, Y., Mottram, J.C., Nelson, S., Ochaya, S., Osoegawa, K., Pai, G., Parsons, M., Pentony, M., Pettersson, U., Pop, M., Ramirez, J.L., Rinta, J., Robertson, L., Salzberg, S.L., Sanchez, D.O., Seyler, A., Sharma, R., Shetty, J., Simpson, A.J., Sisk, E., Tammi, M.T., Tarleton, R., Teixeira, S., Van Aken, S., Vogt, C., Ward, P.N., Wickstead, B., Wortman, J., White, O., Fraser, C.M., Stuart, K.D., & Andersson, B. (2005). The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science, 309(5733), 409-15.
24 Berriman M., Ghedin, E., Hertz-Fowler, C., Blandin, G., Renauld, H., Bartholomeu, D.C., Lennard, N.J., Caler, E., Hamlin, N.E., Haas, B., Bohme, U., Hannick, L., Aslett, M,A., Shallom, J., Marcello, L., Hou, L., Wickstead, B., Alsmark, U.C., Arrowsmith, C., Atkin, R.J., Barron, A.J., Bringaud, F., Brooks, K., Carrington, M., Cherevach, I., Chillingworth, T.J., Churcher, C., Clark, L.N., Corton, C.H., Cronin, A., Davies, R.M., Doggett, J., Djikeng, A., Feldblyum, T., Field, M.C., Fraser, A., Goodhead, I., Hance, Z., Harper, D., Harris, B.R., Hauser, H., Hostetler, J., Ivens, A., Jagels, K., Johnson, D., Johnson, J., Jones, K., Kerhornou, A.X., Koo, H., Larke, N., Landfear, S., Larkin, C., Leech, V., Line, A., Lord, A., Macleod, A., Mooney, P.J., Moule, S., Martin, D.M., Morgan, G.W., Mungall, K., Norbertczak, H., Ormond, D., Pai, G., Peacock, C.S., Peterson, J., Quail, M.A., Rabbinowitsch, E., Rajandream, M.A., Reitter, C., Salzberg, S.L., Sanders, M., Schobel, S., Sharp, S., Simmonds, M., Simpson, A.J., Tallon, L., Turner, C.M., Tait, A., Tivey, A.R., Van Aken, S., Walker, D., Wanless, D., Wang, S., White, B., White, O., Whitehead, S., Woodward, J., Wortman. J., Adams, M.D., Embley, T.M., Gull, K., Ullu, E., Barry, J.D., Fairlamb, A.H., Opperdoes, F., Barrell, B.G., Donelson, J.E., Hall, N., Fraser, C.M., Melville, S.E., & El-Sayed, N.M. (2005). The genome of the African trypanosome Trypanosoma brucei. Science, 309(5733), 416-22.
23 Boonyaratanakornkit, B.B., Simpson, A.J., Whitehead, T.A., Fraser, C.M., El-Sayed, N.M., & Clark, D.S. (2005). Transcriptional profiling of the hyperthermophilic methanarchaeon Methanococcus jannaschii in response to lethal heat and non-lethal cold shock. Environmental Microbiology, 7(6), 789-97.
22 Ouhammouch, M., Langham, G.E.,Hausner, W., Simpson, A.J., El-Sayed, N.M., & Geidushek, P. (2005). Promoter architecture and response to a positive regulator of archaeal transcription. Molecular Microbiology, 56(3), 625-37.
21 Loftus, B., Anderson, I., Davies, R., Alsmark, U.C., Samuelson, J., Amedeo, P., Roncaglia, P., Berriman, M., Hirt, R.P., Mann, B.J., Nozaki, T., Suh, B., Pop, M., Duchene, M., Ackers, J., Tannich, E., Leippe, M., Hofer, M., Bruchhaus, I., Willhoeft, U., Bhattacharya, A., Chillingworth, T., Churcher, C., Hance, Z., Harris, B., Harris, D., Jagels, K., Moule, S., Mungall, K., Ormond, D., Squares, R., Whitehead, S., Quail, M.A., Rabbinowitsch, E., Norbertczak, H., Price, C., Wang, Z., Guillén, N., Gilchrist, C., Stroup, S.E., Bhattacharya, S., Lohia, A., Foster, P.G., Sicheritz-Ponten, T., Weber, C., Singh, U., Mukherjee, C., El-Sayed, N.M., Petri, W.A. Jr., Clark, C.G., Embley, T.M., Barrell, B., Fraser, C.M., & Hall, N. (2005). The genome of the protist parasite Entamoeba histolytica. Nature, 433(7028), 865-8.
20 Kim, D., Chiurillo, M.A., El-Sayed, N.M., Jones, K., Santos, M.R.M, Cerda, P.P., Andersson, B, Myler, P., da Silveira, J.F., & Ramirez, J.L. (2005). Telomere and subtelomere of Trypanosoma cruzi chromosomes are enriched in (pseudo)genes of retrotransposon hot spot and trans-sialidase-like gene families: the origins of T. cruzi telomeres. Gene, 346, 153-61.
19 El-Sayed, N.M., Bartholomeu, D., Ivens, A., Johnston, D.A., & LoVerde, P.T. (2004). Advances in Schistosome genomics. Trends in Parasitology, 20(4), 154-7.
18 LoVerde, P.T., Hirai, H., Merrick, J.M., Lee, N.H., & El-Sayed, N.M.A. (2004). Schistosoma mansoni genome project: an update. Parasitology International, 53(2), 183-192.
17 Ghedin, E., Bringaud, F., Peterson, J., Myler, P., Berriman, M., Ivens, A., Andersson, B., Bontempi, E., Eisen, J., Angiuoli, S., Wanless, D., Von Arx, A., Murphy, L., Lennard, N., Salzberg, S., Adams, M.D., White, O., Hall, N., Stuart, K., Fraser, C.M., & El-Sayed, N.M.A. (2004). Gene synteny and evolution of genome architecture in trypanosomatids. Molecular and Biochemical Parasitology, 143(2), 183-91.
16 Bringaud, F., Biteau, N., Zuiderwijk, Berriman, M., El-Sayed, N.M.A., Ghedin, E., Melville, S.A., Hall, N., & T. Baltz. (2004). The ingi and RIME non-LTR retrotransposons are not randomly distributed in the genome of Trypanosoma brucei. Molecular Biology and Evolution, 21(3), 520-8.
B3 Bartholomeu, D. & El-Sayed, N.M.A. (2004). Sequencing strategies for parasite genomes. In Melville, S.E. (Ed.), Methods in Molecular Biology: Parasite Genomics Protocols (1st ed., pp. 1-16). Humana Press Inc..
15 El-Sayed, N.M.A., Ghedin, E., Song, J., MacLeod, A., Bringaud, F., Larkin, C., Wanless, D., Peterson, J., Hou, L., Taylor, S., Tweedie, A., Biteau, N., Khalak, H.G., Lin, X., Mason, T., Hannick, L., Caler, E., Blandin, G., Bartholomeu, D., Simpson, A.J., Kaul, S., Zhao, H., Pai, G., Van Aken, S., Utterback, T., Haas, B., Koo, H.L., Umayam, L., Suh, B., Gerrard, C., Leech, V., Qi, R., Zhou, S., Schwartz, D., Feldblyum, T., Salzberg, S., Tait, A., Turner, C.M., Ullu, E., White, O., Melville, S., Adams, M.D., Fraser, C.M., & Donelson, J.E. (2003). The sequence and analysis of Trypanosoma brucei chromosome II. Nucleic Acids Research, 31(16), 4856-63.
14 Bartholomeu, D.C., Silva, R.A., Galvão, L.M.C., El-Sayed, N.M.A., Donelson, J.E. & Teixeira, S.M. (2002). Trypanosoma cruzi: RNA structure and post-transcriptional control of tubulin gene expression. Experimental Parasitology, 102(3-4), 123-33.
13 Bringaud, F., Biteau, N., Melville, S.E., Hez, S., El-Sayed, N.M., Leech, V., Berriman, M., Hall, N., Donelson, J.E., & Baltz, T. (2002). A new expressed multigene family containing a hot spot of insertion for retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei. Eukaryotic Cell, 1(1), 137-51.
12 Bringaud, F., Garcia-Pérez, J.L., Heras, S.R., Ghedin, E., El-Sayed, N.M., Andersson, B., Baltz, T., & Lopez, M.C. (2002). Indentification of non-autonomous non-LTR retroposons in the genome of Trypanosoma cruzi. Molecular and Biochemical Parasitology, 124(1-2), 73-8.
11 Diehl, S., Diehl, F., El-Sayed, N.M., Clayton, C., & Hoheisel, J.D. (2002). Analysis of sbadgee-specific gene expression in the bloodstream and the procyclic form of Trypanosoma brucei using a genomic DNA-microarray. Molecular and Biochemical Parasitology, 123(2), 115-123.
10 LaCount, D.J., El-Sayed, N.M., Kaul, S., Wanless, D., Turner, C.M.R., & Donelson, J.E. (2001). Analysis of a donor gene region for a variant surface glycoprotein and its expression site in African trypanosomes. Nucleic Acids Research, 29(10), 2012-9.
9 El-Sayed, N.M.A., Hegde, P., Quackenbush, J., Melville, S.E., & Donelson, J.E. (2000). The African trypanosome genome. International Journal for Parasitology, 30(4), 329-45.
8 Donelson, J.E., Gardner, M.J., & El-Sayed, N.M. (1999). More surprises from Kinetoplastida. PNAS, 96(6), 2579-81.
B2 Donelson, J.E., Hill, K.L., & El-Sayed, N.M.A. (1999). Multiple mechanisms of immune evasion by African trypanosomes. In Pays, E. (Ed.), The Trypanosome Surface (1st ed., pp. 71-91). De Boeck & Larcier S.A..
7 Clayton, C., Adams, M., Almeida, R., Baltz, T., Barrett, M., Bastien, P., Belli, S., Beverley, S., Biteau, N., Blackwell, J., Blaineau, C., Boshart, M., Bringaud, F., Cross, G., Cruz, A., Degrave, W., Donelson, J., El-Sayed, N., Fu, G., Ersfeld, K., Gibson, W., Gull, K., Ivens, A., Kelly, J., Lawson, D., Lebowitz, J., Majiwa, P., Matthews, K., Melville, S., Merlin, G., Michels, P., Myler, P., Norrish, A., Opperdoes, F., Papadopoulou, B., Parsons, M., Seebeck, T., Smith, D., Stuart, K., Turner, M., Ullu, E., & Vanhamme, L. (1998). Genetic nomenclature for Trypanosoma and Leishmania. Mol. Biochem. Parasitol., 97(1-2), 221-4.
6 Donelson, J.E., Hill, K.L., & El-Sayed, N.M.A. (1998). Multiple mechanisms of immune evasion by African trypanosomes. Mol. Biochem. Parasitol., 91(1), 51-66.
5 El-Sayed, N.M.A. & Donelson, J.E. (1997). African trypanosomes have differentially expressed genes encoding homologues of the Leishmania GP63 surface protease. J. Biol. Chem., 272(42), 26742-8.
4 El-Sayed, N.M.A. & Donelson, J.E. (1997). A survey of the Trypanosoma brucei rhodesiense genome using shotgun sequencing. Mol. Biochem. Parasitol., 84(2), 167-78.
3 Morgan, R.W., El-Sayed, N.M.A., Kepa, J.K., Pedram, M., & Donelson, J.E. (1995). Differential expression of the expression site-associated gene I family in African trypanosomes. J. Biol. Chem., 271(16), 9771-7.
2 El-Sayed, N.M.A., Alarcon, C.M., Beck, J.C., Sheffield, V.C. & Donelson, J.E. (1995). cDNA expressed sequence tags of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite. Mol. Biochem. Parasit., 73(1-2), 75-90.
1 El-Sayed, N.M., Harkins, P.C., Fox, R.O., Anderson, K., & Patton, C.L. (1995). Crystallization and preliminary X-ray investigation of the recombinant Trypanosoma brucei rhodesiense calmodulin. Proteins, 21(4), 354-7.